Sm-a-actin
Webbof SM a-actin expression involves a complex interaction of multiple positive and negative cis elements that act in a cell-type specific fashion.10–16 For example, a 547 bp SM a-actin promoter/CAT construct (p547CAT) had high activ-ity in cultured SMCs and in L6 skeletal myotubes, which are cell types that express SM a-actin in culture ... Webb1 jan. 2008 · Alpha-smooth muscle actin (alpha-SMA) is the actin isoform that predominates within vascular smooth-muscle cells and plays an …
Sm-a-actin
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Webb3 dec. 2007 · We identified 2 types of migrating cells with distinctive actin filament structures at the migrating front: type I (Figure (Figure5A), 5 A), cells with a large amount of F-actin stress fibers forming lamellum-like protrusions, and type II (Figure (Figure5A), 5 A), cells with a polarized morphology, a ruffling lamellipodium at the leading edge facing the … Webbimmunocytochemical analysis using antibodies specific for either SM a-actin (Skalli et al., 1986) or SM myosin heavy chain (Kawamoto and Adelstein, 1987). Microscopic evaluation of a number of fields failed to uncover SM a-actin- or SM myosin heavy chain-negative cells (data not shown). Additionally, the expression of SM a-actin in
WebbThe antibody (also known as anti-α-Sm-1) is specific for the single isoform of α-smooth muscle actin. It reacts specifically with α-smooth muscle actin in immunoblotting … Webb21 mars 2024 · GeneCards Summary for ACTA2 Gene. ACTA2 (Actin Alpha 2, Smooth Muscle) is a Protein Coding gene. Diseases associated with ACTA2 include Multisystemic Smooth Muscle Dysfunction Syndrome and Aortic Aneurysm, Familial Thoracic 6 . Among its related pathways are Actin Nucleation by ARP-WASP Complex and Integrin Pathway .
WebbSM a-actin, SM myosin heavy chain (MHC), and h1 calponin. However, induction of SM a-actin by TGF-bis not restricted to SMCs. A study by Shah et al4 demonstrated that TGF-b stimulated differentiation of neural crest cells into SMCs or SMC-like cells based on morphological criteria and the induction of SM a-actin and h1 calponin. Of particular WebbThe Actin Alpha 2 (ACTA2) gene encoding smooth muscle aortic actin, was isolated and characterized. It was found that the ACTA2 gene contains at least 9 exons (7). Alpha smooth muscle actin appears to play an important functional role in myofibroblast contraction and migration.
WebbTransforming growth factor (TGF)-b-induced expression of smooth muscle (SM)-a-actin is accompanied by expression and activation of serum response factor (SRF). (A) Human …
Webb5 feb. 2024 · Actins是球状多功能蛋白质的一个家族，形成微丝。 ACTA2是6种不同肌动蛋白亚型之一，参与平滑肌的收缩。 ACTA2（和所有actins一样）极其保守，几乎在所有哺乳动物中都有发现。 在人类中，ACTA2由位于10q22-q24的ACTA2基因编码。 该基因突变导致多种血管疾病，如胸主动脉疾病、冠状动脉疾病、中风、烟雾病和多系统平滑肌功能障 … song widecombe fairWebbThermo Fisher nonmuscle beta actin emdb emd 27572 arora as huang hl heissler sm chinthalapudi k 2024 cryo em structure Nonmuscle Beta Actin Emdb Emd 27572 Arora As Huang Hl Heissler Sm Chinthalapudi K 2024 Cryo Em Structure, supplied by Thermo Fisher, used in various techniques. Bioz Stars score: 86/100, based on 1 PubMed citations. songwifi noise cancelling headphonesWebbα-Actinin 属于细胞骨架蛋白的血影蛋白家族。 它最早被确认为肌动蛋白交联蛋白，在每个单体的氨基末端与肌动蛋白结合头形成反向平行同型二聚体。 α-actinin 可以与大量参与 … small hand soap dispenser oil bronzedWebbSmooth Muscle Actin ( Figures 25-3, A, and 25-4, A) The smooth muscle actin (SMA) marker has a relatively long track record of use as a myoepithelial marker in breast … song wiki of ice and fireWebbThe cell extracts were analyzed by Western blotting with antibodies against SM-a-actin, SRF, Smad2, Smad4, or b-actin as indicated. (B) Serumstarved human lung fibroblasts … song wide eyed and leglessWebb15 jan. 1992 · Addition of sequence between positions −151 and −257 (p257CAT) resulted in a 7-fold increase in chloramphenicol acetyltransferase activity over that of p151CAT in rat SMC, but not in chicken SMC. A genomic clone encoding the rat smooth muscle alpha-actin gene was isolated, and the 5'-flanking region was partially characterized. small hand tattoo for womenWebbAntibody 1A4 (DAKO) recognizes SM a-actin and was used to detect SMCs, whereas antibody HAM56 (DAKO) was used to recognize macrophages in the sections. Activin was detected with monoclonal antibody E4 (Serotec), and follistatin with an anti-peptide antibody (provided by Prof S. Werner, ETH, Zurich, Swit-zerland). small hand sweeper