Mecbecin
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Mecbecin
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Macbecin belongs to the ansamycin family of antibiotics and was first isolated from actinomycete bacteria. Macbecin possesses potent antitumor properties. In-vitro studies have shown that Macbecin is effective in the eradication of Gram-positive bacteria, fungi, and protozoa including Tetrahymena pyriformis. See more Macbecin has an unusual macrocyclic lactam structure. There are two variants Macbecin I and II which correspond to the oxidized 1,4-benzoquinone and reduced hydroquinone respectively. See more Macbecins mechanism of action is in part due to heat shock protein Hsp90 protein inhibition. See more • Macbecin+I at the US National Library of Medicine Medical Subject Headings (MeSH) • Macbecin+II at the US National Library of Medicine Medical Subject Headings See more
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