Lamp2 lamp2a
TīmeklisLAMP2A functions as a receptor of chaperone-mediated autophagy (CMA), in which cytoplasmic proteins are transported into lysosomes for degradation [ 10 ]. LAMP2B … Tīmeklis2024. gada 9. marts · Lamp-2 deficiency prevents high-fat diet-induced obese diabetes via enhancing energy expenditure. These results suggest that VPS35 deficiency or mutation promotes Parkinson Disease (PD) pathogenesis, and reveals a crucial pathway, VPS35-Lamp2a-alpha-synuclein, to prevent PD pathogenesis.
Lamp2 lamp2a
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Tīmeklis2024. gada 21. marts · LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. Diseases associated with LAMP2 include Danon Disease and Left … Tīmeklis2024. gada 28. marts · 在这项研究中，研究人员发现含有与KFERQ基序相关的氨基酸序列的蛋白质被包装到外泌体的亚群中。 研究人员确定以下几种蛋白是该机制的基本组成部分：溶酶体相关膜蛋白2的同工型A (LAMP2A)，此前被认为是一种将含有KFERQ的底物靶向溶酶体的蛋白质；以及分子伴侣热休克蛋白HSC70。 此外，研究人员证明蛋白 …
Tīmeklis2024. gada 12. nov. · Abstract. Lysosome-associated membrane protein type 2A (LAMP2A) is a key protein in the chaperone-mediated autophagy (CMA) pathway. … TīmeklisThe LAMP2 gene provides instructions for making a protein called lysosomal associated membrane protein-2 (LAMP-2), which, as its name suggests, is found in the …
Tīmeklis2024. gada 8. febr. · LAMP2A decrease enhances the lysosomal damage induced by lysosomotropic agents, ultimately leading to cell death. The effect is cancer-specific, as JNK inhibition does not decrease LAMP2A in... TīmeklisIn this work, we identified and validated 2 NFE2L2 binding sequences in the LAMP2 gene and demonstrated in several human and mouse cell types that NFE2L2 deficiency and overexpression was linked to reduced and increased LAMP2A levels, respectively. Accordingly, lysosomal LAMP2A levels were drastically reduced in nfe2l2-knockout …
TīmeklisLAMP2, together with CD107a/LAMP-1, is a major constituent of lysosomal membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes, and LAMP2 is an important regulator in successful phagosomal maturation.
TīmeklisDescription Rat monoclonal [GL2A7] to LAMP2 Host species Rat Tested applications Suitable for: IHC-Fr, ICC, ICC/IF, IHC-FoFr, IP, Flow Cyt, WB, IHC-P more details Species reactivity Reacts with: Mouse, Rabbit, Human Immunogen Tissue, cells or virus corresponding to Mouse LAMP2. Purified preparation of mouse liver lysosomal … movie theaters in orchard parkTīmeklisSee all LAMP2A primary antibodies Description Rabbit monoclonal [EPR4207 (2)] to LAMP2A - Lysosome Marker Host species Rabbit Tested applications Suitable for: WB, IP, IHC-P, Flow Cyt (Intra), ICC/IF more details Species reactivity Reacts with: Mouse, Rat, Human Immunogen Synthetic peptide. heating pads for cramps cvsTīmeklis购买LAMP2A兔多克隆抗体(ab18528)，LAMP2A抗体经WB验证，可与人,小鼠样本反应。131篇文献引用，15个独立用户反馈。 ... ab18528 staining LAMP2 in MCF7 cells. The cells were fixed with 100% methanol (5 min), permeabilized with 0.1% PBS-Tween for 5 minutes and then blocked with 1% BSA/10% normal goat serum/0.3M ... heating pads for chairsTīmeklisIn this work, we identified and validated 2 NFE2L2 binding sequences in the LAMP2 gene and demonstrated in several human and mouse cell types that NFE2L2 … heating pads for car useTīmeklis2024. gada 27. sept. · LAMP-2 Antibody (H4B4) is an IgG 1 κ mouse monoclonal LAMP-2 antibody (also designated LAMP2 antibody, LAMPB antibody or lysosomal associated membrane protein 2 … movie theaters in palatka flTīmeklisLUXA2 believes that simplicity is the ultimate sophistication. Our design starts from a simple concept. movie theaters in palm beach gardensLAMP-2A is the receptor for chaperone-mediated autophagy. Recently it has been determined that antibodies against LAMP-2 account for a fraction of patients who get a serious kidney disease termed focal necrotizing glomerulonephritis. LAMP-2B is associated with Danon disease . Structure and tissue … Skatīt vairāk Lysosome-associated membrane protein 2 (LAMP2), also known as CD107b (Cluster of Differentiation 107b) and Mac-3, is a human gene. Its protein, LAMP2, is one of the lysosome-associated membrane glycoproteins Skatīt vairāk The gene for LAMP2 has 9 coding exons and 2 alternate last exons, 9a and 9b. When the last exon is spliced with the alternative exon, it is a variant called LAMP2b, which varies in the last 11 amino acids of its C-terminal sequence: in the luminal domain, … Skatīt vairāk • CA77.1 • QX39 Skatīt vairāk • Cluster of differentiation Skatīt vairāk Lysosomes are cell organelles found in most animal cells. Their main functions center around breaking down materials and debris in the cell. Some of this is done via acid … Skatīt vairāk LAMP2 has been specifically implicated in tumor cell metastasis. Both LAMP1 and LAMP2 have been found expressed on the surface of … Skatīt vairāk • Chang MH, Karageorgos LE, Meikle PJ (2003). "CD107a (LAMP-1) and CD107b (LAMP-2)". Journal of Biological Regulators and Homeostatic Agents. 16 (2): 147–51. PMID 12144129. • Schleutker J, Haataja L, Renlund M, Puhakka L, Viitala J, Peltonen L, … Skatīt vairāk movie theaters in panama city beach fl